SKU DS4004 · Fasting Mimicking Diet
L-Biome
L-Biome was developed by scientists at the Longevity Institute at the University of Southern California in collaboration with L-Nutra physicians.
It was designed for the 5-day ProLon post-fast microbiome, from a combination of prebiotics, probiotics and DHA, all in a single daily capsule, thanks to advanced technology.
L-Biome is a supplement designed to maintain a healthy Longevity microbiome. The synergy between Bifidobacterium Breve B3, Lactobacillus Rhamnosus HN001, Inulin and DHA.
- 100% Vegan
- Rich in prebiotics and probiotics
- Supports healthy digestion
- Promotes a healthy intestinal barrier
- Immune health
- Healthy fasting microbiome
- Made in Italy
Nutritional information
| Average content | per 2 capsules | per 3 capsules |
|---|---|---|
| LACTOBACILLUS RHAMNOSUS HN001 | 18 billion CFU | 27 billion CFU |
| BIFIDOBACTERIUM BREVE | 10bn CFU | 15bn CFU |
| OMEGA-3-LYSINE FATTY ACID SALT of which DHA docosahexaenoic acid of which L-lysine |
400 mg 200 mg 132 mg |
600 mg 300 mg 198 mg |
| INULIN | 300 mg | 450 mg |
Ingredients
Omega-3-lysine fatty acid salt (Omega 3 from oil derived from the microalga Schyzochitrium sp., L-lysine), L-Inulin; capsule: Hydroxypropylmethylcellulose; Bifidobacterium breve B3; anti-caking agent: Dicalcium phosphate; Lactobacillus rhamnosus HN001; anti-caking agents: Magnesium salts of fatty acids, Talc; Calcium carbonate.
Warnings
Supplements are not intended as a substitute for a varied and balanced diet and a healthy lifestyle. Do not exceed the recommended daily dose. KEEP OUT OF REACH OF CHILDREN UNDER THREE YEARS OF AGE. Do not take in case of allergies or hypersensitivity to one or more components.
Ships from Lonso Milan facility · 72h after order confirmation · free cold-chain shipping on orders over €1,500.
Post-fast microbiome
Mirrors the beneficial strains that flourish after a 5-day Prolon FMD.
Gut barrier integrity
Lactobacillus rhamnosus HN001 supports a healthy intestinal barrier and gut-immune axis.
Daily routine
Two capsules with a meal. Resume after each refeed day to extend FMD benefits.
How it fits the protocol
Best after a fast. Every day, between cycles.
01
Before the cycle
Optional priming phase — patients can start L-Biome 1 week before their first Prolon FMD to baseline gut microbiota.
02
Day 6 — refeed
Start L-Biome on the morning after the 5-day FMD. This is the moment the post-fasting microbiome is most receptive to new colonisation.
03
Daily, ongoing
Two capsules with a meal. Patients aged 18–80, daily, between FMD cycles or as a long-term gut- health routine.
What's in the capsule
Two probiotics, one prebiotic, plus DHA —the post-FMD microbiome
The quality and rate of our biological aging are the main determinants of a long and healthy life. L-Biome's strength lies in its unique combination of probiotics, prebiotic fibre and DHA that help re-establish a healthy gut microbiome after fasting.
PER 2 CAPS
Per 2 caps
Morinaga B-3®
Bifidobacterium breve B-3
Clinical tests have shown that B-3 reduced fat mass in adults with a tendency to obesity. Supports body weight, blood glucose, insulin and cholesterol levels within a normal range — one of the essential microbiota that develops after the 5-day FMD.
PER 2 CAPS
16 bnCFU
LactoB HN001™
Lactobacillus rhamnosus HN001
Particularly resistant to bile, allowing it to colonise the upper small intestine and colon. Supports healthy digestive function, intestinal barrier integrity, the gut-immune axis, and healthy nutrient absorption — flourishes after Prolon's fasting nutrition.
PER 2 CAPS
1,200 mg
Inulin
Plant-derived prebiotic fibre
Insoluble fibre that nourishes the probiotic flora and promotes its growth. The same prebiotic used inside the 5-day Prolon FMD — addresses the fibre deficit common in modern processed-food diets.
PER 2 CAPS
300 mg
DHA · Algal Oil
Schizochytrium sp.
An essential omega-3 polyunsaturated fatty acid. Structural component of the brain and retina, with positive influence on the gut-brain axis, intestinal wall integrity and immune health. 100% plant-based — sourced from algae, not fish.
DUAL-CAP TECHNOLOGY
Two compartments.
Two release profiles.
One capsule.
L-Biome is equipped with dual-cap technology to ensure that patients get the optimum dosage of each ingredient in a safe and effective way.
Outer shell
DHA, housed for immediate absorption on contact with the digestive tract.
Inner capsule
Probiotic strains and inulin prebiotic fibre — encased and released gradually.
Net result
Patients absorb DHA quickly, then receive steady probiotic and prebiotic support across hours.
Biological Age Score · Nature Aging, 2024
Three cycles. 2.5 years younger, on the data.
In the Mishra et al. 2024 trial (n=144, RCT), patients completing three consecutive Prolon FMD cycles reduced their Levine PhenoAge by an average of 2.5 years versus controls.
3 yrs
Biological Age Δ
−1.30 pp
HBA1C (12 wk)
−7.4%
Trunk Fat
96%
1st-Cycle Completion
- Morinaga B-3® (Bifidobacterium breve B-3): Probiotic strain that supports body weight, blood glucose, insulin and cholesterol within a normal range.
- LactoB HN001™ (Lactobacillus rhamnosus HN001): Bile-resistant probiotic that supports digestive function, gut barrier integrity and the gut-immune axis.
- Inulin: Plant-derived prebiotic fibre that nourishes the probiotic flora and promotes its growth.
- DHA · Algal Oil: Plant-based omega-3 supporting the gut-brain axis, intestinal wall integrity and immune health.
