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Patented, clinically validated longevity products — ready to offer your patients and team.
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Mechanism of action
Prolon 5-Day Fasting Mimicking Diet
A patented, science-backed program that keeps your body in a fasting state while allowing you to eat nourishing foods
Day 1
Glycogen depletion
First 16-24h: hepatic glycogen depletes; insulin drops. Patient enters mild ketosis.
Day 2-3
Ketogenesis
Ketone bodies rise; hypothalamus senses switch to fat-derived fuel.
Day 3-4
Autophagy peak
Cellular cleanup peaks. Senescent cell markers fall, stem-cell activity rises.
Day 5
Stem cell signal
IGF-1 drops 30-40%. Hematopoietic stem cells proliferate; tissue regeneration primed.
Day 6+
Refeed window
Reintroduction window: glucose rebounds with improved sensitivity. Cellular machinery resets.
Expand your product offering, promote well-being and longevity!
ORDER ONLINE
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DEDICATED SUPPORT
We’re always here to help. Our team is available for order support, product training, and more.
PREMIUM PRODUCTS
Prolon is the result of over 25 years of research and development, clinically tested and proven to promote longevity with premium products.
HOW IT WORKS
Get started in four steps.
Create your HCP account
Register as a clinic or healthcare provider and access exclusive prices.
Order Prolon products
Purchase directly for your clinic or for provider use at wholesale prices.
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Give your patients a discount via your personal link and coupon code.
Track your commissions
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ProLon products are the result of research, development and scientific validation.
Fasting Mimicking Technology was a breakthrough in the "Food as Medicine" movement. Using targeted plant-based nutrition, it allows the body to enter a beneficial fasting state… while still eating.
A unique, patented nutritional program, the result of of 20 years and $34 million in scientific research.
#1 Fasting Nutrition Program Recommended by Doctors Worldwide.
Over 1,000,000 kits sold worldwide – join us in promoting a healthier future.
The science
Explore the research
With more than 40 clinical trials published in leading scientific and medical journals worldwide, Prolon's impact is proven by some of the most rigorous nutrition research to date. Browse a selection of our studies below.
The FMD is the only nutrition program supported by preliminary data confirming autophagy activation in humans
A kidney-specific fasting-mimicking diet induces podocyte reprogramming and restores renal function in glomerulopathy
Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk
Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease: controlled trial
Fasting-Mimicking-Diet does not reduce skeletal muscle function in healthy young adults: a randomized control trial
A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
The Effects of a Fasting Mimicking Diet on Skin Hydration, Skin Texture, and Skin Assessment: A Randomized Controlled Trial
Fasting Mimicking Diet Cycles vs a Mediterranean Diet and Cardiometabolic Risk in Overweight and Obese Hypertensive Subjects: A Randomized Clinical Trial
Efficacy of a fasting-mimicking diet in functional therapy for depression: A randomised controlled pilot trial
Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
An Intermittent Fasting Mimicking Nutrition Bar Extends Physiologic Ketosis in Time Restricted Eating: A Randomized, Controlled, Parallel-Arm Study
Association between IGF-1 levels ranges and all-cause mortality: A meta-analysis
Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
Fasting and cancer treatment in humans: A case series report
Fasting-mimicking diet and hormone therapy induce breast cancer regression
Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression
A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control
The clinical workspace
One workspace.
From first prescription to last refeed.
Prescribe in 90 seconds
Initiate, track, and communicate follow-ups built in. Print or e-send the protocol straight to the patient. SNOMed-CT coded.
Monitor cycles remotely
Daily check-ins, side effect flags and vitals alerts. Direct line to L-Nutra Medical Affairs for clinical questions.
Dispense or drop-ship
Hold Prolon stock at wholesale, or have Prolon ship direct from our Italian facility on the day of prescription.
Thanks to technology that simulates fasting, our products help you regain energy and well-being from within.
Find out why more and more people are choosing to fast…while eating.
CELL RENEWAL (AUTOPHAGY)
Autophagy, a "biological miracle" triggered by fasting and awarded the Nobel Prize in Medicine in 2016, is a cellular renewal process essential for vitality, emotional balance, performance, mental clarity, healthy aging, and longevity.
FOCUSED ON THE WEIGHT LOSS
Kickstart weight loss (average 2.5 kg) with targeted action on abdominal fat while maintaining lean mass—ideal for athletes and those seeking high performance. Your body thinks it's fasting, but you're still eating.
CHANGE YOUR RELATIONSHIP WITH FOOD
With ProLon, in 5 days you'll learn to understand and transform your relationship with food. You can feel good and active, even without compulsive eating or overindulging.
GREATER SENSE OF WELL-BEING
Your emotional well-being is one of the great benefits: after ProLon, most people finally feel satisfied unlike long diets that often lead to giving up. You feel more energetic, regenerated, vital, and with a clearer mind.
HEALTHIER SKIN AND YOUNG
Clinically proven to reduce wrinkles and fine lines after 3 ProLon cycles (15 days total). Your skin regenerates from within, an effect users have come to love!
COMFORTABLE, IT ADAPTS TO EVERY LIFESTYLE
Designed for convenience, it fits naturally into any daily routine. Its ready-to-follow format makes wellness simple and adaptable. Comfortable, practical, and easy to integrate into any lifestyle.
Recent publications