The science
Explore the research
With more than 40 clinical trials published in leading scientific and medical journals worldwide, Prolon's impact is proven by some of the most rigorous nutrition research to date. Browse a selection of our studies below.
The FMD is the only nutrition program supported by preliminary data confirming autophagy activation in humans
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A kidney-specific fasting-mimicking diet induces podocyte reprogramming and restores renal function in glomerulopathy
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Fasting-mimicking diet causes hepatic and blood markers changes indicating reduced biological age and disease risk
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Fasting-mimicking diet and markers/risk factors for aging, diabetes, cancer, and cardiovascular disease: controlled trial
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Fasting-Mimicking-Diet does not reduce skeletal muscle function in healthy young adults: a randomized control trial
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A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan
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The Effects of a Fasting Mimicking Diet on Skin Hydration, Skin Texture, and Skin Assessment: A Randomized Controlled Trial
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Fasting Mimicking Diet Cycles vs a Mediterranean Diet and Cardiometabolic Risk in Overweight and Obese Hypertensive Subjects: A Randomized Clinical Trial
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Efficacy of a fasting-mimicking diet in functional therapy for depression: A randomised controlled pilot trial
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Association of Animal and Plant Protein Intake With All-Cause and Cause-Specific Mortality
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An Intermittent Fasting Mimicking Nutrition Bar Extends Physiologic Ketosis in Time Restricted Eating: A Randomized, Controlled, Parallel-Arm Study
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Association between IGF-1 levels ranges and all-cause mortality: A meta-analysis
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Fasting-mimicking diet prevents high-fat diet effect on cardiometabolic risk and lifespan
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Fasting and cancer treatment in humans: A case series report
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Fasting-mimicking diet and hormone therapy induce breast cancer regression
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Nutrition and fasting mimicking diets in the prevention and treatment of autoimmune diseases and immunosenescence
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Fasting-Mimicking Diet Modulates Microbiota and Promotes Intestinal Regeneration to Reduce Inflammatory Bowel Disease Pathology
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Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity
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Prolonged Fasting reduces IGF-1/PKA to promote hematopoietic stem cell-based regeneration and reverse immunosuppression
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A Diet Mimicking Fasting Promotes Regeneration and Reduces Autoimmunity and Multiple Sclerosis Symptoms
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Integration of a fasting-mimicking diet programme in primary care for type 2 diabetes reduces the need for medication and improves glycaemic control
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